Which histology is NOT reportable according to SEER guidelines?

The histology that is not reportable according to SEER guidelines is differentiated exophytic vulvar intraepithelial lesion. Under SEER criteria, certain types of lesions, particularly those that are classified as intraepithelial neoplasia or dysplasia, may not be reportable as they do not meet the threshold for being considered malignant or a definitive precursor lesion that warrants reporting.

In contrast, penile high grade dysplasia, cervical adenocarcinoma in situ associated with HPV, and endometrioid intraepithelial neoplasia are considered reportable because they represent significant precursors to cancer or have been classified as cancerous conditions according to SEER standards. These conditions require tracking as they may progress to invasive cancer, thus representing a necessary focus for cancer registries and public health surveillance. This distinction highlights the importance of knowing which lesions are reportable to ensure accurate cancer statistics and appropriate patient care.